Miranda Paley’s favorite structure is:



Source: PDB


Because: it’s the freaking ribosome! While later structures provided better resolution, this structure is the hallmark of visionary Ada Yonath’s career. She was ridiculed for so many years about trying to crystallize the ribosome, and she finally got it! The additional work on the paper modeling in tetracycline to show its mode of action and to further validate the solution to the structure is also well done. —Miranda Paley

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