Diana Tomchick’s favorite structure is:

PDB ID 1PRC, the photosynthetic reaction center from Rhodopseudomonas viridian


Source: DOI: 10.1006/jmbi.1994.0097


The first atomic resolution structure of an integral membrane protein was a tour de force of protein purification, crystallization and phasing. The resultant structure taught us a huge amount that was generalizable to other integral membrane proteins and about the interaction of proteins with the lipid bilayer. This particular PDB deposition represents the refined coordinates to 2.3 Angstroms resolution, and thus the authors were able to locate associated lipids and solvent molecules in addition to determining the positions of the cofactors and protein side chains.—Diana Tomchick

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