Dr. Gerald E. Wuenschell’s favorite structure is:




PCNA is a molecule of elegant symmetry, with major functionalities distributed in 3-fold fashion around the central “hole” lined with positively charged residues (orange in the image) ideally suited for threading a DNA molecule, with its negative surface, through it when acting as one of its many functions – a sliding clamp.—Dr. Gerald E. Wuenschell

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